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     <div begin="7.566s" end="12.432s">Hi, I’m Tim Peake and welcome on board the International Space Station! </div>
     <div begin="12.433s" end="18.666s">While we are on Earth, we don’t realize how important the pull of gravity is to our overall health. </div>
     <div begin="18.666s" end="26.266s">Up here in space, because we are floating, we have to exercise daily to limit the impact on our cardiovascular system.</div>
     <div begin="26.266s" end="29.966s">In space, the changes to our heart and our blood vessels are quite striking: </div>
     <div begin="29.966s" end="32.666s">did you know that during a six-month space mission, </div>
     <div begin="32.666s" end="37.799s">an astronaut’s cardiovascular system can age by up to 10 or 20 years?</div>
     <div begin="38.766s" end="42.566s">This surprising discovery was made by Professor Richard Hughson, </div>
     <div begin="42.566s" end="46.632s">a Canadian scientist at the University of Waterloo. </div>
     <div begin="46.633s" end="49.366s">With the help of the Canadian Space Agency, </div>
     <div begin="49.366s" end="54.832s">Professor Hughson is currently working on an experiment called Vascular Echo. </div>
     <div begin="54.833s" end="59.366s">This is his fourth study on board the International Space Station. </div>
     <div begin="59.366s" end="65.666s">Vascular Echo examines changes in heart and blood vessels while astronauts are in space, </div>
     <div begin="65.666s" end="69.832s">and monitors their recovery when they return to Earth. </div>
     <div begin="69.833s" end="76.933s">A chronic increase in blood pressure in our head and our neck while in space can result in stiffer arteries.</div>
     <div begin="76.933s" end="81.699s">Changes in our cardiovascular system might also reflect other risk factors, </div>
     <div begin="81.7s" end="87.3s">including the overall reduction in levels of physical activity as we float in space. </div>
     <div begin="87.3s" end="93.333s">This can result in insulin resistance, which is a cause of Type 2 diabetes on Earth.</div>
     <div begin="93.333s" end="98.033s">Nine astronauts will take part in Vascular Echo by providing blood samples </div>
     <div begin="98.033s" end="104.366s">and taking ultrasounds of their arteries before, during and after their missions to space. </div>
     <div begin="104.366s" end="109.232s">The knowledge we gain from Vascular Echo could help keep astronauts healthy in space. </div>
     <div begin="109.233s" end="116.833s">It could also benefit people on Earth, especially those who are sedentary, the elderly, or bedridden patients.</div>
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